Table 1 Comparison between medically responded IIH patients (group I) and those who needed lumbo-peritoneal shunts (group II) at initial baseline assessment visit
Group I (n: 59) | Group II (n: 9) | p vale | ||
|---|---|---|---|---|
Age (years) | 32.72 ± 9.94 | 35.97 ± 5.83 | 0.3449 | |
Body mass index (kg/m2) | 32.76 ± 1.71 | 33.24 ± 1.55 | 0.425 | |
Weight reduction after 6-months (kg) | 14.6 ± 4.2 | 4.4 ± 1.4 | < 0.0001* | |
Headache onset/diagnosis time (days) | 23.58 ± 3.62 | 8.78 ± 3.15 | < 0.0001* | |
Headache severity | 55.37 ± 3.33 | 61.11 ± 3.37 | < 0.0001* | |
Tinnitus severity | 25.89 ± 20.78 | 40.00 ± 17.41 | 0.057 | |
Papilledema grade | Mean ± SD | 1.8 ± 0.64 | 3.2 ± 0.67 | < 0.0001* |
Grade-I | 18 (%) | 0 | < 0.0001* | |
Grade-II | 36 (%) | 1 (%) | ||
Grade-III | 4 (%) | 5 (%) | ||
Grade-IV | 1 (%) | 3 (%) | ||
Opening CSF pressure | 350.49 ± 36.61 | 351.00 ± 35.27 | 0.969 | |
Transient visual obscuration n (%) | 19 (32.2%) | 5 (55.6%) | 0.172 | |
Abducent nerve palsy n (%) | 10 (16.9%) | 3 (33.3%) | 0.244 | |
Empty sella turcica n (%) | 45 (76.3%) | 7 (77.8%) | 0.92 | |
Transverse sinus stenosis n (%) | 27 (45.8%) | 6 (66.7) | 0.243 | |
MD–VFE | Right (decibel) | − 2.9 ± 0.6 | − 3.92 ± 0.44 | < 0.0001* |
Left (decibel) | − 2.7 ± 0.47 | − 3.97 ± 0.48 | < 0.0001* | |
ONSD | Right (mm) | 7.15 ± 0.64 | 7.81 ± 0.62 | 0.0038* |
Left (mm) | 7.16 ± 0.64 | 7.82 ± 0.59 | 0.0052* | |
OCT-RNFL | Right average (μm) | 211.66 ± 53.4 | 288.7 ± 18.25 | < 0.0001* |
Left average (μm) | 209.19 ± 54.03 | 289.19 ± 18.73 | < 0.0001* | |
VEP | Right P100 amplitude (μV) | 11.7 ± 3.8 | 9.8 ± 2.3 | 0.15 |
Left P 100 amplitude (μV) | 11.2 ± 3.4 | 9.6 ± 2.7 | 0.18 | |
Right P100 latency (ms) | 92.78 ± 6.46 | 127.3 ± 7.5 | < 0.0001* | |
Left P 100 latency (ms) | 94.13 ± 6.81 | 127.7 ± 7.2 | < 0.0001* | |