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Table 3 Summary of fNIRS changes in autistic spectrum disorders

From: Translating neuroimaging changes to neuro-endophenotypes of autistic spectrum disorder: a narrative review

Authors

Participants age in years

Task

NIRS result

Brain region

Floyd-Fox et al. [123]

< 1

Auditory and visual task with or without social factors

Activation: ASD < TD

pSTS

Fox et al. [123]

< 1

Face recognition task

Activation: ASD < TD

mPFC, Right TC

Keehn et al. [124]

< 1

resting state while listening sounds

Increased Intra- and inter-hemispheric connectivity in infants with HRA than infants with LRA at 3 months. No difference at 6 and 9 months

TC

Edwards et al. [125]

 

Auditory task

Activation: low-risk female: first-half > second-half high-risk female: first-half = second-half

TC

Zhu et al. [126]

9.0 ± 1.3

Resting state

Intra- and inter-hemispheric connectivity: ASD < TD

TC

Yasumura et al. [127]

10.5 ± 2.3

Stroop task

Reverse Stroop task

Activation: ASD = TD

Right PFC

Xiao et al. [128]

10.1 ± 2.1

Go/No-Go task

Stroop task

Activation: Go/No-go: ASD < TD Stroop: ASD = TD

Right PFC

Minagawa-Kawai et al. [129]

9.2 ± 1.8

Auditory task

Activation: TD: phonemic, left AC; prosodic, right AC ASD: prosodic, right AC

AC

Suda et al. [130]

26.4 ± 3.0

Conversation task

Activation: Negative correlation between activation and Autism Spectrum Quotient score

Left STS

  1. The studies were ordered by ages of individuals with ASD
  2. PFC prefrontal cortex, mPFC medial prefrontal cortex, TC temporal cortex, STS superior temporal sulcus, pSTS posterior superior temporal sulcus, AC auditory cortex