Evaluation of brain structure abnormalities in children with autism spectrum disorder (ASD) using structural magnetic resonance imaging

Table 4 Statistical results of white matter volumetric measurements in Hammers Atlas regions (significant differences)

Brain region	ASD		HC		Mean Difference	P value
	Mean	STD	Mean	STD
L amygdala	0.25	0.03	0.08	0.02	0.16	< 0.001
R amygdala	0.22	0.03	0.12	0.02	0.10	< 0.001
L anterior medial temporal lobe	2.59	0.23	1.56	0.26	1.02	< 0.001
R anterior medial temporal lobe	2.68	0.26	1.67	0.31	1.00	< 0.001
R superior temporal gyrus	6.25	0.61	5.38	0.57	0.87	< 0.001
L inferior middle temporal gyrus	6.47	0.68	5.54	0.63	0.93	< 0.001
R inferior middle temporal gyrus	6.72	0.64	5.69	0.64	1.03	< 0.001
L middle frontal gyrus	24.38	2.62	22.58	2.08	1.80	0.008
R middle frontal gyrus	24.86	2.71	22.73	2.06	1.13	0.002
L posterior temporal lobe	18.98	1.75	17.71	1.52	1.27	0.008
R posterior temporal lobe	19.26	1.73	17.98	1.74	1.28	0.010
L putamen	0.93	0.10	0.53	0.05	0.40	< 0.001
R putamen	1.07	0.10	0.63	0.07	0.43	< 0.001
L thalamus	2.47	0.40	2.68	0.36	− 0.21	< 0.001
R thalamus	2.44	0.29	2.68	0.38	− 0.23	< 0.001
L precentral gyrus	15.73	1.43	16.74	1.75	− 1.01	0.027
L orbitofrontal gyrus	6.71	0.61	5.95	0.56	0.6	< 0.001
R orbitofrontal gyrus	7.07	0.61	6.15	0.70	0.91	< 0.001
L inferior frontal gyrus	6.53	0.84	5.41	0.55	1.11	< 0.001
R inferior frontal gyrus	6.44	0.74	5.51	0.59	0.92	< 0.001

ASD Autism Spectrum Disorder, HC Healthy Controls, STD Standard Deviation, L Left, R Right