Effect of intra-dialytic physical exercise on depression in prevalent hemodialysis patients

Table 5 Univariate and multivariate linear regression analysis for factors affecting HDRS after IDE

HDRS	Univariate					Multivariate
	Unstandardized coefficients		Standardized coefficients	T	P value	Unstandardized coefficients		Standardized coefficients	T	P value
	B	S.E	Beta	T	P value	B	S.E	Beta	T	P value
TNF-α (Pg/ml)	0.107	0.016	0.685	6.515	0.000	0.074	0.019	0.470	3.926	0.000
6MWT (m)	− 0.041	0.012	− 0.441	− 3.406	0.001	0.154	0.063	1.655	2.437	0.019
RAPA	− 2.699	0.514	− 0.604	− 5.254	0.000	− 1.933	0.716	− 0.433	− 2.701	0.010
Peak VO₂ (ml/(kg min)	− 2.011	0.532	− 0.479	− 3.783	0.000	− 6.879	2.944	− 1.639	− 2.337	0.024
Age	0.169	0.075	0.311	2.270	0.028	− 0.050	0.095	− 0.092	− 0.531	0.598
URR %	− 0.228	0.082	− 0.373	− 2.787	0.008	− 0.031	0.066	− 0.051	− 0.470	0.641

HDRS: Hamilton Depression Rating Scale, TNF-α: tumor necrosis factor alpha, 6MWT: six-min walk test, RAPA: rapid assessment of physical activity, peak VO₂: peak volume of oxygen consumption, URR: urea reduction ratio
Bold indicates statistical significance. P value > 0.05: non-significant; P value < 0.05: significant; P value < 0.01: highly significant