Skip to main content
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 2 Changes in ADHD symptoms from baseline to weeks 4–7 to 9–12

From: Functional outcomes of extended-release methylphenidate and atomoxetine in children: retrospective chart analysis

 

OROS-MPH

ATX

Slope difference between OROS-MPH and ATX

Estimate

SE

95%CI

Cohen’s da

Estimate

SE

95%CI

Cohen’s da

Estimate

SE

95% CI

t value

Cohen’s da

LL

UL

LL

UL

LL

UL

Week 4–7 to baseline

 T-DSM-IV-S scores

  Total

22.333***

0.404

21.360

23.307

2.647

2.082

0.939

− 0.201

4.365

0.143

− 20.199***

0.857

− 21.882

− 18.515

23.557

1.012

  İnattention

13.203***

0.392

12.260

14.146

1.613

0.911

0.494

− 0.283

2.105

0.119

− 12.321***

0.790

− 13.873

− 10.769

15.585

0.669

  Hyperactivity/impulsivity

8.936***

0.320

8.166

9.707

1.337

1.027

0.871

− 1.085

3.139

0.076

− 7.877***

0.753

− 9.357

− 6.398

10.454

0.449

  Oppositional defiance

0.079

0.471

− 1.506

1.214

0.008

− 0.240

0.570

− 1.618

1.139

0.028

0.304

0.764

− 1.807

1.199

0.398

0.017

  Conduct disorder

0.427

0.249

− 0.173

1.027

0.082

0.250

0.364

− 0.631

1.131

0.044

0.184

0.425

− 1.021

1.199

0.435

0.018

Week 9–12 to 4–7

 T-DSM-IV-S scores

  Total

4.473***

0.509

3.244

5.701

0.471

12.893***

1.215

9.947

15.840

0.762

8.498***

0.947

6.632

10.364

8.969

0.345

  İnattention

2.968***

0.423

1.948

3.988

0.376

7.617***

0.645

6.049

9.184

0.848

4.782***

0.532

3.734

5.831

8.987

0.345

  Hyperactivity/impulsivity

1.632

0.277

− 0.962

2.301

0.315

5.369***

0.989

2.970

7.769

0.390

3.717***

0.803

2.135

5.299

4.625

0.178

  Oppositional defiance

0.793

0.560

− 0.557

2.143

0.075

3.666***

0.542

2.351

4.980

0.485

2.703**

0.849

1.030

4.376

3.183

0.122

  Conduct disorder

1.463***

0.242

0.881

2.045

0.324

2.856***

0.286

2.161

3.551

0.717

1.368***

0.341

0.697

2.039

4.009

0.154

Week 9–12 to baseline

 T-DSM-IV-S scores

  Total

26.806***

0.462

25.691

27.921

2.941

14.975***

0.892

12.805

17.146

1.109

− 6.125***

0.490

− 7.088

− 5.161

12.492

0.503

  İnattention

16.171***

0.428

15.142

17.200

1.918

8.527***

0.723

6.777

10.277

0.779

− 3.917***

0.410

− 4.725

− 3.110

9.545

0.384

  Hyperactivity/impulsivity

10.568***

0.368

9.684

11.452

1.458

6.396***

0.710

4.678

8.114

0.595

− 2.085***

0.367

− 2.807

− 1.362

5.678

0.228

  Oppositional defiance

0.872

0.603

− 0.580

2.323

0.073

3.426***

0.512

2.191

4.662

0.442

1.196**

0.374

0.460

1.933

3.199

0.128

  Conduct disorder

1.890***

0.258

1.270

2.510

0.372

3.107***

0.285

2.419

3.794

0.712

0.617**

0.208

0.206

1.028

2.957

0.119

  1. SE standard errors, d Cohen’s d for effect size, β parameter estimates of the slope of changes over time, ADHD attention-deficit/hyperactivity disorder, ATX atomoxetine, OROS-MPH osmotic-release oral delivery system methylphenidate, T-DSM-IV-S the Turgay DSM-IV Disruptive Behavior Disorders Rating Scale
  2. aCohen’s d calculation was based on; M or β divided by standard deviation of M or β *p < 0.05, **p < 0.01, ***p < 0.001
Back to article page