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Table 4 Comparison of etiologies of peripheral neuropathies with four other studies

From: Etiological profile of peripheral neuropathies in an academic hospital in southern Morocco

 

Our cohort (n = 180)

Egypt [9] (n = 1343)

Norway [12] (n = 226)

Netherlands [5] (n = 743)

Meta-analysis [8] (n = 2613)

Diabetes

26.7%

20.40%

18%

32%

34%

Inflammatory

27.2%

0.74%

16%a

9%c

13%c

 APRN

26.1%

0.37%

12%

 CPRN

1.1%

0.37%

4%

ALS

16.1%

Immunological disease

5.6%

4%

5%

4%

Idiopathic

5%

2.90%

28%

26%

23%

Medication

5%f

Infectious

3.9%

0.74%

2%

Hereditary

0.37%b

14%b

5%

6%

Friedreich’s disease

2.8%

0.22%

Alcohol

2.2%

10%

Paraneoplastic

1.7%

0.07%

3%

Critical illness polyneuropathy

1.7%

Deficiency neuropathy

1.1%

4%

4%

3%

Amyloid

0.6%

Toxic

0.6%

14%d

13%d

Metabolic

21.89%e

4%e

4%e

Hypoythroidism

0.37%

4%

Liver disease

0.45%

1%

  1. aInflammatory neuropathy = APRN, CPRN
  2. bHereditary causes such as Charcot-Marie-Tooth were not found in our study; for reference 9, figure represents only Charcot-Marie-Tooth
  3. cChronic inflammatory demyelinating polyneuropathy, Guillain–Barré syndrome, polyneuropathy associated with monoclonal gammopathy of undetermined significance, polyneuropathy associated with malignancy/neuronal paraneoplastic antibodies, and HIV, Lyme disease, leprosy-associated polyneuropathy
  4. dVasculitic neuropathy, amyloid neuropathy, sarcoid neuropathy, and polyneuropathy with connective tissue disease, such as Sjögren disease and rheumatoid arthritis
  5. eUremic polyneuropathy and neuropathy related to thyroid dysfunction, renal failure, and liver disease
  6. fMedication-induced neuropathy in our study was due to cisplatine in 5 patients and isoniazide in 4 patients