Skip to main content

Table 1 Characteristics of metformin and non-metformin groups

From: Association between vitamin B12 level and clinical peripheral neuropathy in type 2 diabetic patients on metformin therapy

Variables

Non-metformin group n = 50

Metformin group n = 50

P value

Gender

   

 Female

39 (78%)

32 (64%)

0.123

 Male

11 (22%)

18 (36%)

 

Age (years)

53.3 ± 7.9

53.2 ± 7.2

0.926

Diabetes duration (years)

6.3 ± 5.0

7.3 ± 5.1

0.295

Estimated vitamin B12 daily intake (mcg)

7.1 ± 16.5

5.4 ± 4.5

0.535

Adequacy of vitamin B12 daily intake (≥ 2.4 mcg) n (%)

36 (72%)

35 (70%)

0.826

Serum vitamin B12 (pg/ml)

991.0 ± 489.9

624.3 ± 364.1

 < 0.001

Vitamin B12 deficiency n (%)

1 (2%)

2 (4%)

1.000

HbA1c (%)

8.6 ± 2.3

7.6 ± 2.0

0.03

Peripheral Neuropathy frequency n (%)

32 (64%)

36 (72%)

0.391

TCSS neuropathy score

7.7 ± 3.7

7.8 ± 3.4

0.910

TCSS grade

   

Normal (0–5)

18 (36%)

14 (28%)

 

Mild (6–8)

12 (24%)

17 (34%)

0.452

Moderate (9–11)

14 (28%)

10 (20%)

 

Sever (12–19)

6 (12%)

9 (18%)

 
  1. P value < 0.05 significant; P value < 0.01 highly significant
  2. TCSS Toronto Clinical Scoring System