Skip to main content

Table 3 Showing mean ± SD of Nissl granules density, area % of GFAP positive astrocytes, trabecular bone thickness and percentage of trabecular bone volume in different groups

From: Effects of tamoxifen alone and in combination with risperidone on hyperlocomotion, hippocampal structure and bone in ketamine-induced model of psychosis in rats

 

Nissl’s granules density

Area % of GFAP positive astrocytes

Trabecular bone thickness (µm)

Percentage of trabecular bone volume

Control/non-ketamine treated

9 6 ± 1.1

1.86 ± 0.81

151.9 ± 5.1

46.7 ± 3.3

Control/ketamine treated

66.4 ± 1.51*

34.78 ± 1.83*

143.5 ± 4.3

39.5 ± 4.4

TAM/ketamine treated

81.6 ± 1.1*,#

17.76 ± 1.67*,#

139.7 ± 5.7

36.7 ± 3.1

RISP/ketamine treated

88 ± 1.6*,#

12.34 ± 0.91*,#

79.4 ± 3.2*,#

12.4 ± 1.4*,#

TAM/RISP/ketamine treated

93.6 ± 1.2#,ɫ

7.21 ± 0.68*,#,ɫ

113.5 ± 4.4*,#,ɫ

30.7 ± 3.6*,#,ɫ

  1. Tam tamoxifen; Risp risperidone; GFAP glial fibrillary acidic protein
  2. *p < 0.05 significant compared to control non-ketamine treated
  3. #p < 0.05 significant drug treated ketamine compared to control/ketamine
  4. ɫp < 0.05 significant compared to Risp/ketamine treated