Animal groups n = 10 | BDNF hippocampus ng/g tissue | Oxidative stress markers | |||
---|---|---|---|---|---|
Hippocampus | Bone | ||||
GSH pg/g tissue | MDA ng/g tissue | GSH pg/g tissue | MDA ng/g tissue | ||
Control non-ketamine treated | 10.2 ± 0.31 | 10.55 ± 0.42 | 1.6 ± 0.2 | 6.5 ± 0.35 | 1.49 ± 0.15 |
Control/ketamine | 1.94 ± 0.1* | 1.54 ± 0.18* | 10.93 ± 0.5* | 3.28 ± 0.19* | 5.2 ± 0.25* |
TAM/ketamine | 6.35 ± 0.34*,#,ɫ | 5.5 ± 0.25*,#,ɫ | 4.5 ± 0.5*,#,ɫ | 5.66 ± 0.29#,ɫ | 2.26 ± 0.1#,ɫ |
Risp/ketamine | 4.8 ± 0.22*,# | 3.6 ± 0.22*,# | 7.03 ± 0.48*,# | 0.88 ± 0.15*,# | 7.5 ± 0.29*,# |
TAM/Risp/ketamine | 7.66 ± 0.25*,#,ɫ | 7.8 ± 0.33*,#,ɫ | 4.6 ± 0.25*,#,ɫ | 5.01 ± 0.3*#,ɫ | 3.19 ± 0.133*,#,ɫ |