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Fig. 1 | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Fig. 1

From: Effects of tamoxifen alone and in combination with risperidone on hyperlocomotion, hippocampal structure and bone in ketamine-induced model of psychosis in rats

Fig. 1

H&E stained sections of hippocampus (CA3) region. A Control non ketamine treated rats showed pyramidal layer is formed of large pyramidal cells having vesicular nuclei. B Ketamine treated rats showed many shrunken pyramidal cells with dark cytoplasm and pyknotic nuclei. C Tamoxifen/ketamine treated group showed some pyramidal cells were shrunken with pyknotic nuclei. D Risperidone/ketamine treated rats showed very few cells having dark pyknotic nuclei. E Tamoxifen/risperidone/ketamine treated rats showed most pyramidal cells were nearly comparable to control

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