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Table 2 Comparison between patients with MS and healthy controls

From: Correlation between functional MRI techniques and early disability in ambulatory patients with relapsing–remitting MS

 

Patients with MS

N = 80

Control

N = 20

P value

Age (year)

33.20 ± 8.6

33.5 ± 10.5

0.144

Sex

  

0.687

 Male

36 (45)

8(40)

 

 Female

44 (55)

12 (60)

 

EDSS

  

 < 0.001

 No disability

28 (35.0%)

0 (0.0%)

 

 Minimal

32 (40.0%)

0 (0.0%)

 

 Moderate disability

20 (25.0%)

0 (0.0%)

 

EDSS Score (mean ± SD)

2.4 ± 1.2

0.0 ± 0.0

 

Non-conventional MRI finding

(mean ± SD)

   

 ADC

1.37 ± 0.03

0.815 ± 0.039

 < 0.001

 NAA/Cr NAWM

1.60 ± 0.39

2.27 ± 0.24

0.017

 NAA/Cr (plaque)

1.38 ± 0.46

  

 Cho/NAA_NAWM

0.67 ± 0.08

0.60 ± 0.052

0.020

 Cho/NAA (plaque)

.7270 ± .08860

  

 Cho/Cr NAWM

1.01 ± 0.308

0.88 ± 0.049

0.001

 Cho/Cr (plaque)

1.0875 ± .0302

  
  1. Cho/Cr choline/creatine; Cho/NAA choline/N-acetyl-aspartate; EDSS expanded disability status scale; NAA/Cr N-acetyl-aspartate/creatine; NAWM normal appearing white matter