Baseline predictors of progression of Parkinson’s disease in a sample of Egyptian patients: clinical and biochemical

Table 5 Correlations between progression of motor and physical activity with laboratory and imaging characteristics

Absolute change between baseline and 1-year follow-up		HbA1c%^a	Uric acid (mg/dL)	Cholesterol (mg/dL)	Triglycerides mg/dL)^a	LDL (mg/dL)	HDL (mg/dL)^a	Fazekas total^a	Scheltens total^a
Δ MDS-UPDRS total score OFF	Pearson	0.027	0.102	0.226	− 0.056	0.295	− 0.113	− 0.084	− 0.003
	Sig	0.865	0.532	0.161	0.731	0.065	0.498	0.592	0.985
Δ Axial OFF^a	Spearman	0.000	0.209	0.133	0.056	0.256	− 0.064	0.002	0.028
Δ Axial OFF^a	Sig	0.998	0.196	0.415	0.733	0.110	0.701	0.990	0.859
Δ PIGD OFF^a	Spearman	− 0.194	0.276	0.171	0.230	0.322	− 0.068	− 0.089	0.004
Δ PIGD OFF^a	Sig	0.224	0.084	0.292	0.154	0.043	0.685	0.571	0.978
Δ Motor complication total score^a	Spearman	− 0.217	− 0.111	0.065	0.313	0.013	− 0.050	− 0.146	− 0.059
Δ Motor complication total score^a	Sig	0.172	0.495	0.691	0.049	0.939	0.766	0.350	0.704
Δ Hoehn and Yahr OFF^a	Spearman	0.198	0.148	0.122	− 0.151	0.139	− 0.005	0.041	0.105
Δ Hoehn and Yahr OFF^a	Sig	0.215	0.362	0.452	0.351	0.393	0.976	0.795	0.496
Δ Schwab and England ADL OFF^a	Spearman	0.113	0.020	− 0.113	− 0.102	− 0.086	0.051	− 0.019	0.096
Δ Schwab and England ADL OFF^a	Sig	0.482	0.902	0.487	0.532	0.598	0.760	0.901	0.537
Δ IPAQ	Pearson	0.066	0.009	− 0.014	0.027	0.018	0.023	0.086	− 0.136
Δ IPAQ	Sig	0.683	0.958	0.933	0.867	0.912	0.891	0.582	0.379

Bold values are significant
LDL low-density lipoproteins, HDL = high-density lipoproteins, MDS-UPDRS Movement Disorder Society—Unified Parkinson’s Disease Rating Scale PIGD = postural instability and gait disorder, ADL activities of daily living, IPAQ International Physical Activity Questionnaire
^*p value is significant if < 0.05
^**After Bonferroni correction, p value is significant if < 0.003