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Table 3 Regression analysis between concentration of IgA, IgM and IgG anti-HP antibodies with EDSS, age and length of disease

From: Helicobacter pylori antibodies and multiple sclerosis: a single-center study and a short review of the literature

IgG (RU/ml) Univariate Multivariate
Coef 95% CI Coef 95% CI
EDSSa − 0.04 − 0.1 to 0.09 − 0.1 − 0.3 to 0.01
Age − 0.4 − 1.3 to 0.4 − 0.81 − 1.7 to 0.1
Length of disease 0.1 − 0.9 to 1.3 − 0.3 − 1.2 to 1.1
IgM (RU/ml) Univariate Multivariate
Coef 95% CI Coef 95% CI
EDSSa − 0.1 − 0.2 to 0.1 − 0.1 − 0.2 to 0.06
Age − 0.07 − 0.1 to -0.005 − 0.06 − 0.1 to 0.01
Length of disease − 0.02 − 0.1 to 0.06 − 0.01 − 0.1 to 0.08
IgA (RU/ml) Univariate Multivariate
Coef 95% CI Coef 95% CI
EDSSa 0.04 − 0.1 to 0.1 − 0.04 − 0.2 to 0.1
Age − 0.0004 − 0.01 to 0.01 − 0.006 − 0.02 to 0.01
Length of disease 0.001 − 0.01 to 0.02 − 0.001 − 0.02 to 0.02
  1. Phenotype of multiple sclerosis, sex, and previous history of immunomodulatory agents were used as covariates for the multivariate analysis
  2. RU/ml Relative units per milliliter; EDSS Expanded disability status scale; Coef Regression coefficient; 95% CI 95% confidence interval
  3. aEDSS was considered as an ordinal variable and ordinal linear regression was conducted for this case