The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 3 Regression analysis between concentration of IgA, IgM and IgG anti-HP antibodies with EDSS, age and length of disease

From: Helicobacter pylori antibodies and multiple sclerosis: a single-center study and a short review of the literature

IgG (RU/ml)	Univariate		Multivariate
IgG (RU/ml)	Coef	95% CI	Coef	95% CI
EDSS^a	− 0.04	− 0.1 to 0.09	− 0.1	− 0.3 to 0.01
Age	− 0.4	− 1.3 to 0.4	− 0.81	− 1.7 to 0.1
Length of disease	0.1	− 0.9 to 1.3	− 0.3	− 1.2 to 1.1

IgM (RU/ml)	Univariate		Multivariate
IgM (RU/ml)	Coef	95% CI	Coef	95% CI
EDSS^a	− 0.1	− 0.2 to 0.1	− 0.1	− 0.2 to 0.06
Age	− 0.07	− 0.1 to -0.005	− 0.06	− 0.1 to 0.01
Length of disease	− 0.02	− 0.1 to 0.06	− 0.01	− 0.1 to 0.08

IgA (RU/ml)	Univariate		Multivariate
IgA (RU/ml)	Coef	95% CI	Coef	95% CI
EDSS^a	0.04	− 0.1 to 0.1	− 0.04	− 0.2 to 0.1
Age	− 0.0004	− 0.01 to 0.01	− 0.006	− 0.02 to 0.01
Length of disease	0.001	− 0.01 to 0.02	− 0.001	− 0.02 to 0.02

Phenotype of multiple sclerosis, sex, and previous history of immunomodulatory agents were used as covariates for the multivariate analysis
RU/ml Relative units per milliliter; EDSS Expanded disability status scale; Coef Regression coefficient; 95% CI 95% confidence interval
^aEDSS was considered as an ordinal variable and ordinal linear regression was conducted for this case

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