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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 2 Analysis of association between, results of IgA, IgM and IgG anti-HP antibodies with MS phenotype

From: Helicobacter pylori antibodies and multiple sclerosis: a single-center study and a short review of the literature

IgG positive

Univariate

Multivariate

OR

95% CI

OR

95% CI

Type of MS

RRMS (base)

–

–

–

–

PPMS

0.75

0.19–2.9

1.08

0.25–4.6

SPMS

2.1

0.72–6.6

4.7

1.1–19.6

IgM positive

Univariate

Multivariate

OR

95% CI

OR

95% CI

Type of MS

RRMS (base)

–

–

–

–

PPMS

0.25

0.03–2.1

0.39

0.04–3.3

SPMS

–

–

–

–

IgA positive

Univariate

Multivariate

OR

95% CI

OR

95% CI

Type of MS

RRMS (base)

–

–

–

–

PPMS

1.0

0.34–3.2

1.0

0.33–3.3

SPMS

1.6

0.57–4.9

2.02

0.57–7.1

  1. Age, sex, length of disease and previous history of immunomodulatory agents were used as covariates for the multivariate analysis
  2. RRMS relapsing–remitting multiple sclerosis; PPMS primary-progressive multiple sclerosis; SPMS: secondary progressive multiple sclerosis; OR odds ratio; 95% CI 95% confidence interval
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