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Table 2 Copy number of gut microbiota among Parkinson’s disease patients and control group

From: Gut microbiota in Parkinson’s disease patients: hospital-based study

 

Total PD patients (n = 46)

PD patients under treatments (n = 39)

Newly diagnosed (non-treated patients) (n = 7)

Control (n = 31)

P-value

Total PD versus controls

Treated PD versus controls

Newly PD versus controls

Newly versus treated patients

Clostridium cluster IV

11.5 ± 3.7

11.9 ± 3.7

9.8 ± 4.3

8.04 ± 1.38

< 0.001

< 0.001

0.39

0.378

Firmicutes

7.6 ± 2.3

7.3 ± 2.2

9.0 ± 2.7

9.64 ± 1.89

< 0.001

< 0.001

0.90

0.061

Akkermansia

8.0 ± 1.9

8.3 ± 1.9

6.5 ± 0.97

6.75 ± 1.92

0.012

0.005

1.0

0.043

Bifidobacterium

10.8 ± 1.4

10.7 ± 1.4

11.4 ± 1.2

9.36 ± 1.69

< 0.001

0.006

0.004

0.238

Lactic acid bacteria

12.4 ± 2.1

12.3 ± 2.3

13.3 ± 2.2

9.98 ± 3.84

0.003

0.04

0.022

0.289

  1. PD Parkinson’s disease