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Table 2 Demographic and clinical factors associated with the most commonly used drugs for neuropathic pain

From: Dispensing patterns of drugs used for neuropathic pain and adherence to NeuPSIG guideline: an observational study

Evaluated factors

First-line agents

OR (95% CI)

Opioids

OR (95% CI)

NSAIDs

OR (95% CI)

Age

0.96 (0.93–0.98)

0.98 (0.95–1.01)

1.03 (1.01–1.05)

Female (ref male)

0.46 (0.21–1.00)

1.36 (0.61–3.01)

0.45 (0.26–0.79)

Diabetes mellitus

0.75 (0.24–2.32)

3.38 (0.69–16.58)

0.75 (0.24–2.32)

Anxiety

0.34 (0.09–1.27)

1.00 (0.29–3.38)

0.67 (0.26–1.69)

Depression

1.16 (0.47–2.89)

1.00 (0.41–2.44)

0.99 (0.53–1.82)

Alcohol intake

0.41 (0.19–0.90)

2.32 (1.01–5.35)

0.96 (0.52–1.77)

Smoking status

0.89 (0.42–1.86)

3.59 (1.46–8.81)

0.56 (0.32–1.00)

Diabetic neuropathy

6.27 (1.72–22.82)

0.05 (0.004–0.62)

1.09 (0.25–4.75)

Post-herpetic neuralgia

6.15 (0.78–47.99)

0.14 (0.01–1.57)

1.31 (0.33–5.20)

Cervical/lumbar radiculopathy

2.74 (0.46–16.16)

0.05 (0.008–0.34)

2.63 (0.97–7.12)

Spinal cord injury

3.00 (0.46–19.26)

0.99 (0.16–6.11)

2.33 (0.74–7.29)

Neuropathic post-operative pain

1.78 (0.24–12.86)

0.79 (0.12–5.14)

1.01 (0.28–3.61)

Trigeminal neuralgia

0.55 (0.05–7.50)

0.75 (0.04–11.60)

0.00 (0.00–)

Post traumatic neuralgia

1.02 (0.99–5.57)

1.14 (0.15–8.27)

1.20 (0.30–4.79)

Prescribed by a physician

23.33 (9.36–58.11)

5.17 (1.02–25.95)

0.10 (0.03–0.26)

  1. CI confidence interval, NSAIDs nonsteroidal anti-inflammatory drugs, OR odds ratio
  2. p < 0.05