Skip to main content

Table 4 Relapse rates before, during, and after pregnancy

From: Outcomes of pregnancy in Egyptian women with multiple sclerosis in the new treatment era: a multi-center retrospective observational study

 

No. pregnancies

No. relapses

Rate of relapse/pregnancies/ya

P value*

2 years before pregnancy

63

84

0.36 (0.32–0.41)

Pregnancy

    

 First trimester

2

2

0.07 (0.04–0.15)

 < 0.001

 Second trimester

3

3

0.10 (0.03–0.17)

 < 0.001

 Third trimester

6

6

0.15 (0.08–0.24)

 < 0.001

Year after pregnancy

    

 Months 1–3

8

8

0.27 (0.16–0.39)

0.037

 Months 4–6

11

11

0.38 (0.26–0.52)

0.990

 Months 7–9

10

11

0.38 (0.26–0.52)

0.751

 Months 10–12

7

7

0.24 (0.17–0.38)

0.023

  1. aMean and 95% confidence intervals
  2. *Compared with 2 years before pregnancy, generalized estimation equations were used to account for women with multiple pregnancies. Level of significance is set when the P-value < 0.05