| |
Cortical (N = 10)
|
Subcortical (N = 12)
|
Cortical–subcortical (N = 28)
|
Control (N = 30)
|
P
|
P1
|
P1
|
P3
|
|---|
|
Right median nerve
|
|
N20 amplitude
|
2.1 ± 0.6
|
1.9 ± 0.7
|
1.9 ± 0.8
|
2.2 ± 0.8
|
0.62
|
0.86
|
0.25
|
0.25
|
|
N20 latency
|
23.2 ± 0.1
|
23.2 ± 0.1
|
23.3 ± 0.2
|
23.3 ± 0.2
|
0.28
|
0.08
|
0.536
|
0.96
|
|
P24 amplitude
|
20.9 ± 27.5
|
7.2 ± 1.9
|
3.29 ± 2.4
|
2.7 ± 0.8
|
0.005*
|
< 0.001*
|
< 0.001*
|
0.004*
|
|
P24 latency
|
24.8 ± 0.6
|
25.2 ± 0.8
|
25.1 ± 0.3
|
25.2 ± 0.2
|
0.3
|
0.14
|
0.864
|
0.61
|
|
N33 amplitude
|
24.5 ± 30.8
|
9.7 ± 1.8
|
4.4 ± 2.9
|
3.9 ± 1.3
|
0.004*
|
0.006*
|
< 0.001*
|
0.005*
|
|
N33 latency
|
33.5 ± 0.2
|
34.1 ± 0.5
|
34.1 ± 0.4
|
34.1 ± 0.2
|
0.003*
|
< 0.001*
|
0.89
|
0.87
|
|
P24–N33 complex amp
|
45.4 ± 58.3
|
16.5 ± 3.4
|
7.7 ± 5.2
|
5.8 ± 1.9
|
0.004*
|
< 0.001*
|
< 0.001*
|
0.002*
|
|
Left median nerve
|
|
N20 amplitude
|
2 ± 0.7
|
2.1 ± 0.7
|
1.9 ± 0.7
|
2.1 ± 0.7
|
0.76
|
0.89
|
0.25
|
0.48
|
|
N20 latency
|
23.2 ± 0.1
|
23.3 ± 0.1
|
23.2 ± 0.1
|
23.2 ± 0.2
|
0.05
|
0.14
|
0.54
|
0.86
|
|
P24 amplitude
|
19.4 ± 22.5
|
7.3 ± 2.3
|
3.3 ± 1.9
|
2.4 ± 0.9
|
0.002*
|
0.041*
|
< 0.001*
|
0.034*
|
|
P24 latency
|
25.2 ± 0.9
|
24.9 ± 0.2
|
25.1 ± 0.1
|
25.2 ± 0.2
|
0.39
|
0.83
|
0.86
|
0.11
|
|
N33 amplitude
|
23.5 ± 26.5
|
8.8 ± 2.69
|
4.6 ± 2.2
|
3.5 ± 1.3
|
0.002*
|
0.041*
|
< 0.001*
|
0.029*
|
|
N33 latency
|
33.6 ± 0.6
|
33.97 ± 0.52
|
34.1 ± 0.3
|
34.1 ± 0.2
|
0.104
|
0.040*
|
0.895
|
0.746
|
|
P24–N33 complex amp
|
42.9 ± 49
|
16.1 ± 4.9
|
7.9 ± 4
|
5.7 ± 2
|
0.002*
|
0.040*
|
< 0.001*
|
0.024*
|
|
EEG Spike/polyspike wave complex
|
10 (100%)
|
4 (33.3%)
|
18 (64.3%)
|
0
|
0.005*
|
< 0.001
|
< 0.001
|
< 0.001
|
- P: all patients according to anatomical subtypes vs control (one-way Anova test); P1: cortical myoclonus vs control (Student t-test); P2: subcortical myoclonus vs control (Student t-test); P3: cortical–subcortical myoclonus vs control (Student t-test)
