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Table 3 Ultrasonography assessment and MRI results of all studied groups

From: Signs of neuroinflammation outweigh neurodegeneration as predictors for early conversion to MS

  Group 1 Group 2   CIS group  
CIS
N=22
1st attack MS
N=20
p-value MS convertors
N=9
MS non-convertors
N=13
p-value
Brain imaging       
 T2 MRI brain lesions Typical 11 (50%) 20 (100%) *0.003 7 (77.8%) 4 (30.8%) 0.08
Atypical 11 (50%) 0 (0%) 2 (22.2%) 9 (69.2%)
 T1 black holes ≥1 5 (22.7%) 15 (75%) *0.004 3 (33.3%) 2 (15.4%) 0.502
 Total number of lesions (mean ±SD) 4.86±4.20 9.65±3.79 *0.001 6.22±4.89 3.92±3.55 0.357
Patients with MRI enhancing lesions 5 (22.7%) 15 (75%) *0.001 3 (33.3%) 2 (15.4%) 0.841
 Substantia nigra echogenicity Normal 11 (55%) 15 (75%) 0.2 2 (25%) 9 (75%) 0.06
Hypoechogenic 9 (45%) 5 (25%) 6 (75%) 3 (25%)
 Ventricular diameter 3rd ventricle Normal (%) 14 (66.7%) 17 (85%) 0.277 5 (62.5%) 9 (69.2%) 1
Dilated (%) 7 (33.3%) 3 (15%) 3 (37.5%) 4 (30.8%)
Frontal horn Median (cm) 0.19 0.22 0.916 0.19 0.19 0.600
Dilated (%) 5 (25%) 2 (10.5%) 0.661 3 (37.5%) 2 (16.7%) 0.255