Skip to main content

Table 5 Association between demographic, clinical, and MRI characteristics and cognitive dysfunction in MS and NMOSD patients

From: A comparison of cognitive performances between neuromyelitis optica spectrum disorder and multiple sclerosis patients in Indian context

Characteristic MS
(FAB)
NMOSD (FAB) MS (no. of cognitive domains involved) NMOSD (no. of cognitive domains involved) MS (no. of executive subdomains involved) NMOSD (no. of executive subdomains involved)
  r p r p r p r p r p r p
Age − .315 .048 − .309 .185 .446 .004 .197 .404 .309 .053 .238 .311
Gender (female) NA .339 NA .009 NA .068 NA .009 NA .086 NA .531
Formal education in years .301 .051 .385 .093 .358 .023 − .263 .261 0.632 < .0001 − .283 .227
Disease duration − .021 .898 .284 .224 .158 .332 − .029 .902 .219 .175 .044 .854
No. of relapses .146 .368 .233 .323 − .125 .443 − .060 .802 − .279 .175 − .114 .633
EDSS .101 .534 .704 .001 − .097 .550 .514 .020 − .134 .410 .240 .308
MRI lesion load .386 .014 − .040 .867 .268 .094 .232 .325 .292 .068 .176 .457
OCB positivity NA .012 NA NA NA < .0001 NA NA NA < .0001 NA NA
  1. The associations were calculated by Pearson’s correlation coefficient and chi square tests. r value is correlation coefficient. p value ≤ 0.05 considered statistically significant