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Table 4 Diagnostic performance of MRI and MRV findings in discriminating IIH cases from control

From: Diagnostic value of brain MR imaging and its correlation with clinical presentation and cognitive functions in idiopathic intracranial hypertension patients

 

TP

FP

TN

FN

SN

SP

PPV

NPV

Accuracy

MRI findings

1- Decrease pituitary gland height

29

3

31

5

85.2%

91.2%

90.6%

86.1%

88.2%

2- Flattened posterior globe

26

0

34

8

76.4%

100%

100%

80.9%

88.2%

3- Optic-nerve sheath distention

29

3

31

5

85.2%

91.1

90.6%

86.1%

88.2%

4-Optic nerve tortuosity

9

0

34

25

26.5%

100%

100%

57.6%

63.2%

Combined MRI findings (presence of 3 or more MRI findings)

29

0

34

5

85.2%

100%

100%

87.1%

92.2%

MRV findings

Transverse/sigmoid sinus patency

• Unilateral stenosis vs. normal

11

4

30

8

57.9%

88.2%

73.3%

78.9%

77.3%

• Bilateral stenosis vs. normal

15

0

33

8

65.2%

100%

100%

80.5%

85.7%

• Abnormal vs. normal

26

4

30

8

76.5%

88.2%

86.6%

78.9%

82.3%

Combined conduit score (CCS)

29

2

32

5

85.3%

94.1%

93.5%

84.2%

89.7%

  1. MRI, magnetic resonance imaging; MRV, magnetic resonance venography; TP, true positive; FP, false positive; TN, true negative; FN, false negative; SN, sensitivity; SP, specificity; PPV, positive predictive value; NPV, negative predictive value; FPOS, flat posterior optic sclera