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Table 3 Association between BDNF and characteristics of the MDD group

From: Serum BDNF and suicidal ideation in drug-naïve and drug-treated MDD patients: a case–control study

Variables

BDNF (ng/ml)

P

HDRS total score

P

Median

Range

Median

Range

Sex

 Males

13.7

12.6–13.9

0.04

16

15–28

0.04

 Females

12.9

4.3–13.3

S

17

11–29

S

Marital status

 Married

12.6

4.3–13.9

0.1

25

15–29

˂0.001

 Not married

13.7

13.3–13.9

 

16

11–19

HS

Education

 Illiterate, elementary

13.7

11.0–13.9

0.08

16

11–25

0.001

 Preparatory, secondary

12.9

11.5–13.9

 

19

16–27

S

 High education

12.8

4.3–13.7

 

21

16–29

 

Occupation

 Working

12.9

12.6–13.9

0.09

19

15–28

0.5

 Not working

12.9

4.3–13.9

 

16

11–29

 

Family history

 Positive

12.9

4.3–13.9

0.04

16

11–29

˂0.001

 Negative

13.2

11.0–13.7

S

21

19–28

HS

Compliance with treatment

 Yes

13.7

12.6–13.9

0.04

16

11–29

˂0.001

 No

12.9

4.3–13.3

S

22

19–28

H.S.

Suicidal ideation

 BSS < 24

13.7

13.6–13.7

˂0.001

16

11–29

˂0.001

 BSS ≥24

11.0

4.3–11.5

HS

22

19–28

HS

Subgroups

 Drug-naïve patients

12.6

4.3–13.7

˂0.001

25

11–29

< 0.001

 Drug-treated patients

13.7

12.6–13.9

HS

16

11–28

(HS)

  1. BDNF serum level of brain-derived neurotrophic factor, HDRS Hamilton Depression Rating Scale, BSS Beck Scale for Suicidal Ideation, S significant, HS highly significant