From: Serum BDNF and suicidal ideation in drug-naïve and drug-treated MDD patients: a case–control study
Variables | BDNF (ng/ml) | P | HDRS total score | P | ||
---|---|---|---|---|---|---|
Median | Range | Median | Range | |||
Sex | ||||||
Males | 13.7 | 12.6–13.9 | 0.04 | 16 | 15–28 | 0.04 |
Females | 12.9 | 4.3–13.3 | S | 17 | 11–29 | S |
Marital status | ||||||
Married | 12.6 | 4.3–13.9 | 0.1 | 25 | 15–29 | ˂0.001 |
Not married | 13.7 | 13.3–13.9 | 16 | 11–19 | HS | |
Education | ||||||
Illiterate, elementary | 13.7 | 11.0–13.9 | 0.08 | 16 | 11–25 | 0.001 |
Preparatory, secondary | 12.9 | 11.5–13.9 | 19 | 16–27 | S | |
High education | 12.8 | 4.3–13.7 | 21 | 16–29 | ||
Occupation | ||||||
Working | 12.9 | 12.6–13.9 | 0.09 | 19 | 15–28 | 0.5 |
Not working | 12.9 | 4.3–13.9 | 16 | 11–29 | ||
Family history | ||||||
Positive | 12.9 | 4.3–13.9 | 0.04 | 16 | 11–29 | ˂0.001 |
Negative | 13.2 | 11.0–13.7 | S | 21 | 19–28 | HS |
Compliance with treatment | ||||||
Yes | 13.7 | 12.6–13.9 | 0.04 | 16 | 11–29 | ˂0.001 |
No | 12.9 | 4.3–13.3 | S | 22 | 19–28 | H.S. |
Suicidal ideation | ||||||
BSS < 24 | 13.7 | 13.6–13.7 | ˂0.001 | 16 | 11–29 | ˂0.001 |
BSS ≥24 | 11.0 | 4.3–11.5 | HS | 22 | 19–28 | HS |
Subgroups | ||||||
Drug-naïve patients | 12.6 | 4.3–13.7 | ˂0.001 | 25 | 11–29 | < 0.001 |
Drug-treated patients | 13.7 | 12.6–13.9 | HS | 16 | 11–28 | (HS) |