Intravenous thrombolysis outcome in posterior vs anterior circulation stroke in a tertiary stroke center in Egypt

Table 2 Comparison of the distribution of OTD and DTN, NIHSS at different time points, intracranial hemorrhage and death and their significance between the two study groups

	Site				t test
	Anterior circulation stroke		Posterior circulation stroke		t test
	Mean	SD	Mean	SD	p value
OTD (hour)	2.1	0.8	2.1	0.7	0.9
DTN (min)	50.6	22.3	45.6	19.9	0.1
NIHSS Pre r-tPA	10.5	4.6	7.7	4.4	<0.001*
NIHSS 2 h	8.8	4.9	6.1	4.2	<0.001*
NIHSS 24 h	7.7	5.0	5.2	4.0	<0.001*
NIHSS 7 days	6.4	4.8	4.3	3.9	0.001*
Repeated measure ANOVA	<0.001*		<0.001*
	Anterior		Posterior		Chi-square test p value
ICH	N	%	N	%	Chi-square test p value
No	97	82.2%	17	85.0%	0.76
Yes	21	17.8%	3	15.0%	0.76
Death					Fisher exact test p value
No	283	97.60%	61	100.00%	0.61
Yes	7	2.40%	0	0.00%	0.61

*Significant
OTD onset-to-door, DTN door-to-needle, SD standard deviation, MIN minute, NIHSS National Institute of Health Stroke Scale, ICH intracranial hemorrhage