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Table 1 Comparative risk homozygous haplotype regions among overall landscape and specific to autism

From: Risk homozygous haplotype regions for autism identifies population-specific ten genes for numerous pathways

Sample type Category Risk haplotype homozygous regions overall landscape Risk haplotype homozygous regions-autism specific
Chromo somal location Max score rHH regions count Genes identified number Chromosomal loci Max score* rHH
regions count
Associated genes identified
Autism Trios using Affymetrix Mapping 250k Nsp SNP Array A1 2,4,7,8,
11,12
4500-5700 12 29 8: 50280717-50921942 5714 6 SNTG1-RELN
11:49038697-49228613 4645 FOLH1
11:48086151-48110043 4603 PTPRJ-JAK2
12:88808147-89252667 5154 KITLG
12:88459309-88681867 4592 CEP290, KITLG
Autism Trios using Affymetrix Mapping 250k Sty SNP Array A2 2,8,9,10 4000-5000 11 102 16:31716601-46710869 4827 6 SLC6A10P,TP53TG3,TP53TG3B
Autism cases Yoruba HapMap genotype as Controls using Affymetrix Mapping 250k Nsp SNP Array B1 4,8,11 21000-24000 9 28 8:50280717-50808334 24275 3 SNTG1-RELN
11:49038697-49295867 21801 FOLH1
11:48168664-48293931 21778 PTPRJ-JAK2
Autism cases Yoruba HapMap genotype as Controls using Affymetrix Mapping 250k Sty SNP Array B2 3,11,16 18268 6 145 3:51880614-52047421 18268 3 ACY1, ABHD14A
  1. *Threshold level of significance (P = 0.05) is scored at 4000 and above; max block length = 1000
  2. **Genes in bold are previously known autism genes