Fig. 2
From: A review on SARS-CoV-2 and stroke pathogenesis and outcome
SARS-CoV 2 effect on endothelial cell and vessel wall. SARS-CoV-2 entrance to cells through ACE 2 receptors with down regulation of ACE 2 receptors and on replication and emergence from cells endothelial damage takes place with either vessel wall rupture or vessel lumen narrowing up to occlusion by thrombus, unopposed angiotensin II causes elevation in blood pressure that may cause hemorrhagic or ischemic strokes