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Table 2 The baseline clinical characteristics of MS patients

From: Serum level of brain-derived neurotrophic factor in patients with relapsing–remitting multiple sclerosis: a potential biomarker for disease activity

Clinical characteristics

MS cases in remission (n = 30)

MS cases in relapse (n = 30)

P value

Age of onset (years)

  

0.938

 Mean ± SD

26.5 ± 7.7

26.6 ± 7.1

 Range (min–max)

(15–40)

(15–44)

Duration of illness (years)

  

0.478

 Mean ± SD

5.1 ± 4.7

4.3 ± 4.3

 Range (min–max)

(1–17)

(1–18)

Number of relapses in the last 2 years

  

0.580

 Mean ± SD

1.5 ± 0.7

1.6 ± 0.6

 Range (min–max)

(0–3)

(1–3)

Total number of relapses

  

0.371

 Mean ± SD

3.1 ± 1.9

2.1 ± 1.4

 Range (min–max)

(1–8)

(1–6)

EDSS

  

0.970

 Mean ± SD

2.89 ± 1.3

2.95 ± 1.6

 Range (min–max)

(1–5)

(1–7)

Immunomodulatory therapy no. (%)

  

0.045*

 Monthly methylprednisolone

17 (56.7%)

21 (70%)

 Intramuscular interferon beta-1a

7 (23.3%)

1 (3.3%)

 Subcutaneous interferon beta-1b

2 (6.7%)

6 (20%)

 Subcutaneous interferon beta-1a

4 (13.3%)

2 (6.7%)

  1. MS Multiple Sclerosis, EDSS Expanded Disability Status Scale
  2. *P value < 0.05 (significant)