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Table 2 The baseline clinical characteristics of MS patients

From: Serum level of brain-derived neurotrophic factor in patients with relapsing–remitting multiple sclerosis: a potential biomarker for disease activity

Clinical characteristics MS cases in remission (n = 30) MS cases in relapse (n = 30) P value
Age of onset (years)    0.938
 Mean ± SD 26.5 ± 7.7 26.6 ± 7.1
 Range (min–max) (15–40) (15–44)
Duration of illness (years)    0.478
 Mean ± SD 5.1 ± 4.7 4.3 ± 4.3
 Range (min–max) (1–17) (1–18)
Number of relapses in the last 2 years    0.580
 Mean ± SD 1.5 ± 0.7 1.6 ± 0.6
 Range (min–max) (0–3) (1–3)
Total number of relapses    0.371
 Mean ± SD 3.1 ± 1.9 2.1 ± 1.4
 Range (min–max) (1–8) (1–6)
EDSS    0.970
 Mean ± SD 2.89 ± 1.3 2.95 ± 1.6
 Range (min–max) (1–5) (1–7)
Immunomodulatory therapy no. (%)    0.045*
 Monthly methylprednisolone 17 (56.7%) 21 (70%)
 Intramuscular interferon beta-1a 7 (23.3%) 1 (3.3%)
 Subcutaneous interferon beta-1b 2 (6.7%) 6 (20%)
 Subcutaneous interferon beta-1a 4 (13.3%) 2 (6.7%)
  1. MS Multiple Sclerosis, EDSS Expanded Disability Status Scale
  2. *P value < 0.05 (significant)