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Table 1 Comparison between patients with favorable and unfavorable outcomes regarding inflammatory biomarkers, stroke severity, and short-term outcome

From: Role of some inflammatory biomarkers in prediction of short-term outcome in acute ischemic stroke

Variables Favorable outcome patients Unfavorable outcome patients Test of sig. P value
Age (years), mean ± SD 63.3 ± 10.2 65.8 ± 10.2 T
0.9
0.3
Sex
Male 12 (50%) 14 (38.9%) χ2
0.724
0.395
Female 12 (50%) 22 (61.1%)
Smoking
Yes 3 (12.5%) 5 (13.9%) Fisher
0.02
0.877
No 21 (87.5%) 31 (86.1%)
Hypertension
Yes 20 (83.3%) 31 (86.1%) Fisher
0.087
0.768
No 4 (16.7%) 5 (13.9%)
Diabetes
Yes 13 (54.2%) 21 (58.3%) χ2
0.102
0.750
No 11 (45.8%) 15 (41.7%)
Obesity
Yes 1 (4.2%) 4 (11.1%) Fisher
0.909
0.340
No 23 (95.8%) 32 (85.9%)
Ischemic heart
Yes 6 (25%) 10 (27.8%) χ2
0.057
0.812
No 18 (75%) 26 (27.8%)
Transient ischemic attack
Yes 9 (37.5%) 11 (30.6%) χ2
0.313
0.576
No 15 (62.5%) 25 (69.4%)
Atrial fibrillation
Yes 3 (12.5%) 12 (33.3%) χ2
3.33
0.068
No 21 (87.5%) 24 (66.7%)
Dyslipidemia
Yes 7 (29.2%) 11 (30.6%) χ2
0.013
0.908
No 17 (70.8%) 25 (69.4%)
Glasgow Coma Scale
Mild (>13) 14 (58.3%) 1 (2.8%) χ2
23.7
15.3
Fisher
<0.001**
Moderate (9–13) 10 (41.7%) 32 (88.9%) <0.001**
Severe (3–8) 0 (0.0%) 3 (8.3%) 0.2
NIHSS, median (range) 6 (5–16) 15 (8–21) MW
5.9
<0.001**
White blood cell count (× 103/μL), median (IQ range) 9.9 (6.4–11.1) 10.8 (7.5–13.1) MW
3.6
0.04*
Neutrophil/lymphocyte ratio, median (IQ range) 2.5 (1.8–4.1) 5.2 (2.9–7.7) MW
3.6
0.04*
C-reactive protein (mg/L), median (IQ range) 16.7 (5.2–46.7) 35.0 (19.2–83.0) MW
2.2
0.02*
Erythrocyte sedimentation rate (mm), median (IQ range) 30.0 (20.0–55.8) 37.5 (23.5–57.5) MW
1.0
0.3
Surrounding edema
Yes 0 (0.0%) 10 (27.8%) χ2
8.0
0.005*
No 24 (100%) 26 (72.2%)
Size of infarction
Small 16 (66.7%) 4 (11.1%) 20 <0.001**
Medium 7 (29.2%) 14 (38.9%) 0.6 0.4
Large 1 (4.2%) 18 (50.0%) 14 <0.001**
  1. IQ interquartile, MW Mann-Whitney, χ2 chi-square test, T T test, NIHSS National Institute of Health Stroke Scale
  2. **Highly significant
  3. *Significant