Table 3 Comparison between the different groups at baseline and follow-up periods according to different thyroid profile parameters

TSH^#

Total

n = 48

n = 48

n = 48

Median (min.–max.)

1.2 (0.3–11)

1.3 (0.4–5.2)

1 (0.3–5.2)

0.062

Mean ± SD

1.6 ± 1.7

1.4 ± 1

1.4 ± 1.1

Avonex

n = 8

n = 8

n = 8

Median (min.–max.)

1.7 (0.3–11)

0.8 (0.5–5.2)

0.8 (0.5–5.2)

0.446

Mean ± SD

2.9 ± 3.5

1.8 ± 1.8

1.7 ± 1.8

Betaferon

n = 19

n = 19

n = 19

Median (min.–max.)

0.8 (0.3–2.9)

0.8 (0.4–3)

0.7 (0.3–3)

0.692

Mean ± SD

1.1 ± 0.7

1.1 ± 0.8

1.1 ± 0.8

Rebeif

n = 21

n = 21

n = 21

Median (min.–max.)

1.4 (0.4–3.5)

1.6 (0.4–3.3)

1.8 (0.3–3)

0.028*

Mean ± SD

1.5 ± 0.8

1.6 ± 0.7

1.6 ± 0.9

FT3^$

Total

n = 48

n = 48

n = 48

Median (min.–max.)

3.1 (1.2–3.8)

3.2 (1.8–3.9)

3.3 (1.8–3.9)

0.007*

Mean ± SD

3.0 ± 0.5

3.1 ± 0.4

3.2 ± 0.4

Avonex

n = 8

n = 8

n = 8

Median (min.–ax.)

3.1 (1.2–3.8)

2.9 (2.4–3.7)

3.1 (2.4–3.7)

0.408

Mean ± SD

2.8 ± 0.8

2.9 ± 0.4

3.1 ± 0.4

Betaferon

n = 19

n = 19

n = 19

Median (min.–max.)

3.2 (2–3.7)

3.3 (1.8–3.9)

3.3 (1.8–3.9)

0.101

Mean ± SD

3.1 ± 0.4

3.2 ± 0.5

3.2 ± 0.5

Rebeif

n = 21

n = 21

n = 21

Median (min.–max.)

3 (2–3.5)

3.2 (2.2–3.6)

3.3 (2.2–3.6)

0.028*

Mean ± SD

3 ± 0.4

3.2 ± 0.3

3.2 ± 0.4

FT4^$

Total

n = 48

n = 48

n = 48

Median (min.–max.)

1.2 (0.3–1.9)

1.2 (0.8–1.9)

1.2 (0.8–1.9)

0.303

Mean ± SD

1.2 ± 0.3

1.2 ± 0.3

1.2 ± 0.3

Avonex

n = 8

n = 8

n = 8

Median (min.–max.)

1.2 (0.3–1.5)

1.3 (0.8–1.9)

1.3 (0.8–1.9)

0.398

Mean ± SD

1.1 ± 0.4

1.3 ± 0.3

1.3 ± 0.3

Betaferon

n = 19

n = 19

n = 19

Median (min.–max.)

1.2 (0.7–1.8)

1.1 (0.9–1.8)

1.1 (0.9–1.9)

0.615

Mean ± SD

1.2 ± 0.3

1.2 ± 0.3

1.2 ± 0.3

Rebeif

n = 21

n = 21

n = 21

Median (min.–max.)

1.2 (0.8–1.9)

1.2 (0.8–1.9)

1.2 (0.8–1.9)

0.826

Mean ± SD

1.2 ± 0.3

1.2 ± 0.2

1.2 ± 0.2