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Table 6 Agreement (sensitivity, specificity) for serum level of neuron-specific enolase (NSE) and clinical severity of stroke (NIHSS)predict mortality (n = 6)

From: Validity of neuron-specific enolase as a prognostic tool in acute ischemic stroke in adults at Suez Canal University Hospital

NSE AUC p 95% C.I Cutoffa Sensitivity Specificity PPV NPV
NSE at presentation 0.836 0.010* 0.642–1.030 > 33.45 66.67 96.77 80.0 93.7
NSE at 48 h 0.855 0.007* 0.690–1.019 > 31.04 66.67 93.55 66.7 93.5
NIHSS at presentation 0.978 < 0.001* 0.938–1.019 > 19 100.0 90.32 66.7 100.0
  1. AUC, area under a curve; p value, probability value; CI, confidence intervals; NPV, negative predictive value; PPV, positive predictive value; NSE, neuron-specific enolase; NIHSS, National Institutes of Health Stroke Scale
  2. *Statistically significant at p ≤ 0.05
  3. aCutoff was chosen according to Youden index