Table 4 Comparison between the serum level of neuron-specific enolase (NSE) and the clinical severity of stroke (NIHSS) among the patients (n = 37)

 Mean ± SD

24.9 ± 8.8

23.1 ± 8.1

34.5 ± 6.2

U = 30.50*

0.007*

 Median (Min.–Max.)

27.8 (12.7–42.1)

26.7 (12.7–35.3)

36.6 (26.8–42.1)

 Mean ± SD

24.0 ± 8.4

22.3 ± 7.7

33.0 ± 5.5

U = 27.0*

0.005*

 Median (Min.–Max.)

27.2 (11.6–41.0)

24.4 (11.6–33.5)

33.2 (25.7–41.0)

^Zp₁

0.002*

0.013*

0.046*

 Moderate stroke (5–15)

15 (40.5%)

15 (48.4%)

0 (0.0%)

χ² = 4.883

^FEp = 0.063

 Moderate to severe stroke (16–20)

17 (45.9%)

15 (48.4%)

2 (33.3%)

χ² = 0.459

^FEp = 0.667

 Severe stroke ≥ 21

5 (13.5%)

1 (3.2%)

4 (66.7%)

χ² = 17.311*

^FEp = 0.001*

 Mean ± SD

16.4 ± 4.6

15.1 ± 3.5

23.5 ± 3.1

t = 5.517*

< 0.001*

 Median (Min.–Max.)

16.0 (10.0–28.0)

16.0 (10.0–22.0)

24.0 (20.0–28.0)

 Moderate stroke (5–15)

20 (54.1%)

20 (64.5%)

0 (0.0%)

χ² = 8.425*

^FEp = 0.005*

 Moderate to severe stroke (16–20)

11 (29.7%)

11 (35.5%)

0 (0.0%)

χ² = 3.030*

^FEp = 0.151

 Severe stroke ≥ 21

6 (16.2%)

0 (0.0%)

6 (100.0%)

χ² = 37.0*

^FEp < 0.001*

 Mean ± SD

15.6 ± 5.8

13.7 ± 3.8

25.7 ± 3.2

t = 7.152*

< 0.001*

 Median (Min.–Max.)

14.0 (7.0–30.0)

13.0 (7.0–20.0)

26.0 (22.0–30.0)

^tp₁

0.008*

< 0.001*

0.003*