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Table 4 Relation between metabolic syndrome components, HOMA-IR and EDSS scores among MS patients

From: Impact of insulin resistance and metabolic syndrome on disability in patients with multiple sclerosis

Metabolic syndrome items

EDSS score (mean ± SD)

p value

Fasting glucose

  ≥ 100 mg/dL

2.8 ± 1.4

0.3

  ≤ 100 mg/dL

3.3 ± 1.3

Blood pressure

  ≥ 130/85 mmHg

2.9 ± 1.3

0.6

  ≤ 130/85 mmHg

3.1 ± 1.4

Triglycerides

  ≥ 150 mg/dL

3.01 ± 1.4

0.5

  ≤ 150 mg/dL

2.6 ± 0.56

HDL-C

  < 40 mg/dL in men or < 50 mg/dL in women

3.2 ± 1.6

0.2

  > 40 mg/dL in men or > 50 mg/dL in women

2.6 ± 0.67

Waist circumference

  ≥ 102 cm in men or ≥ 88 cm in women

2.9 ± 1.5

0.8

  ≤ 102 cm in men or ≤ 88 cm in women

3 ± 1.1

Metabolic syndrome

 No

2.9 ± 1.5

0.7

 Yes

2.8 ± 0.8

HOMA-IR

 Normal

3.1 ± 1.6

0.3

 Abnormal

2.7 ± 1

  1. HDL-C High-density lipoprotein cholesterol, HOMA-IR The homeostasis model assessment for insulin resistance