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Table 5 Correlation between gender, stroke type, hemorrhagic conversion of stroke and midline shift, and the functional outcome of AIS

From: Predictors of the functional outcome after thrombolysis in an Egyptian patients’ sample

 

Δ Change of NIHSS

(initial–after 6 months)

mRS after 6 months

Δ Change of mRS

(after 24 h–after 6 months)

Mean ± SD

Test of sig.

P

Mean ± SD

Median

Test of sig.

P

Mean ± SD

Test of sig.

P

Sex

 Male

5.47 ± 1.77

U = 92.0*

0.024*

2.80 ± 2.42

3

U = 272

0.607

0.35 ± 1.14

U = 214.50

0.402

 Female

7.27 ± 3.98

  

2.36 ± 2.18

1

  

0.72 ± 1.57

  

Initial CT brain (MCA sign)

 Negative

6.58 ± 3.39

U = 10.0

0.450

2.51 ± 2.25

2

U = 55.50

0.517

0.60 ± 1.40

U = 20.50

0.201

 Positive

5.0

3.50 ± 3.54

3.5

0.50 ± 0.71

Anterior vs. posterior circulation

 Anterior circulation

6.39 ± 3.27

U = 2.636

0.104

2.51 ± 2.25

2

U = 55.50

0.517

0.58 ± 1.40

U = 33.50

0.618

 Posterior circulation

12.0

3.50 ± 3.53

3.5

0.0 ± 1.41

TOAST classification

 Cardioembolic LVO

8.11 ± 4.68

H = 4.645

0.200

3.73 ± 2.34

4

H = 14.27*

0.003*

0.20 ± 1.82

H = 4.787

0.188

 Atherosclerotic LVO

4.88 ± 2.70

3.30 ± 2.21

4

0.50 ± 1.65

 Small vessel stroke

6.50 ± 1.83

0.67 ± 1.15

0

0.92 ± 0.79

 Undetermined cause

6.50 ± 3.74

2.25 ± 1.75

1

0.75 ± 0.71

Hemorrhagic transformation

 Negative

6.76 ± 3.34

U = 46.50

0.354

2.28 ± 2.22

1

U = 176.50*

0.045*

0.72 ± 1.41

U = 49.50*

0.021*

 Positive

4.75 ± 3.40

4.33 ± 1.86

4.5

− 0.50 ± 0.55

Midline shift

 No midline shift

7.06 ± 3.08

H = 5.020

0.081

2.03 ± 2.16

1

H = 9.129*

0.010*

0.83 ± 1.38

H = 8.583*

0.014*

 Midline shift < 5

4.60 ± 3.58

4.43 ± 1.40

4

− 0.57 ± 0.79

 Midline shift > 5

0.0

5.50 ± 0.71

5.5

− 0.50 ± 0.71

  1. U Mann Whitney test, H Kruskal Wallis test, AIS acute ischemic stroke, Δ Change rate of change, NIHSS National Institutes of Health Stroke Scale, mRS modified Ranking score, CT computed tomography, MCA middle cerebral artery, TOAST classification trial of ORG 10172 in acute stroke treatment classification, LVO large vessel occlusion
  2. P = P value for comparing between the different categories
  3. * Statistically significant at p ≤ 0.05