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Table 5 Correlation between gender, stroke type, hemorrhagic conversion of stroke and midline shift, and the functional outcome of AIS

From: Predictors of the functional outcome after thrombolysis in an Egyptian patients’ sample

  Δ Change of NIHSS
(initial–after 6 months)
mRS after 6 months Δ Change of mRS
(after 24 h–after 6 months)
Mean ± SD Test of sig. P Mean ± SD Median Test of sig. P Mean ± SD Test of sig. P
Sex
 Male 5.47 ± 1.77 U = 92.0* 0.024* 2.80 ± 2.42 3 U = 272 0.607 0.35 ± 1.14 U = 214.50 0.402
 Female 7.27 ± 3.98    2.36 ± 2.18 1    0.72 ± 1.57   
Initial CT brain (MCA sign)
 Negative 6.58 ± 3.39 U = 10.0 0.450 2.51 ± 2.25 2 U = 55.50 0.517 0.60 ± 1.40 U = 20.50 0.201
 Positive 5.0 3.50 ± 3.54 3.5 0.50 ± 0.71
Anterior vs. posterior circulation
 Anterior circulation 6.39 ± 3.27 U = 2.636 0.104 2.51 ± 2.25 2 U = 55.50 0.517 0.58 ± 1.40 U = 33.50 0.618
 Posterior circulation 12.0 3.50 ± 3.53 3.5 0.0 ± 1.41
TOAST classification
 Cardioembolic LVO 8.11 ± 4.68 H = 4.645 0.200 3.73 ± 2.34 4 H = 14.27* 0.003* 0.20 ± 1.82 H = 4.787 0.188
 Atherosclerotic LVO 4.88 ± 2.70 3.30 ± 2.21 4 0.50 ± 1.65
 Small vessel stroke 6.50 ± 1.83 0.67 ± 1.15 0 0.92 ± 0.79
 Undetermined cause 6.50 ± 3.74 2.25 ± 1.75 1 0.75 ± 0.71
Hemorrhagic transformation
 Negative 6.76 ± 3.34 U = 46.50 0.354 2.28 ± 2.22 1 U = 176.50* 0.045* 0.72 ± 1.41 U = 49.50* 0.021*
 Positive 4.75 ± 3.40 4.33 ± 1.86 4.5 − 0.50 ± 0.55
Midline shift
 No midline shift 7.06 ± 3.08 H = 5.020 0.081 2.03 ± 2.16 1 H = 9.129* 0.010* 0.83 ± 1.38 H = 8.583* 0.014*
 Midline shift < 5 4.60 ± 3.58 4.43 ± 1.40 4 − 0.57 ± 0.79
 Midline shift > 5 0.0 5.50 ± 0.71 5.5 − 0.50 ± 0.71
  1. U Mann Whitney test, H Kruskal Wallis test, AIS acute ischemic stroke, Δ Change rate of change, NIHSS National Institutes of Health Stroke Scale, mRS modified Ranking score, CT computed tomography, MCA middle cerebral artery, TOAST classification trial of ORG 10172 in acute stroke treatment classification, LVO large vessel occlusion
  2. P = P value for comparing between the different categories
  3. * Statistically significant at p ≤ 0.05