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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Fig. 1 | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Fig. 1

From: Pain as clinical manifestations of COVID-19 infection and its management in the pandemic era: a literature review

Fig. 1

The mechanism of COVID-19 attacking the nervous system through ACE2 distribution [34]. (a) COVID-19 virus enter the brain circulation. (b) The virus particles will damage the endothelial lining thus supporting the virus to go through the brain. (c) COVID-19 virus will spread to the circulation or via the cribriform plate of the ethmoid bone. (d) The virus then will interact with the ACE2 receptor

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