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Table 3 Comparison between Parkinson’s disease patients with and without depression and those with and without anxiety in demographic and clinical criteria

From: Depression and anxiety among patients with Parkinson’s disease: frequency, risk factors, and impact on quality of life

Characteristic

PD with depression

N = 20

PD without depression

N = 44

P value

PD with anxiety

N = 26

PD without anxiety

N = 38

P value

Age at onset (mean ± SD)

64.4 ± 7.8

67.1 ± 9.5

0.155

61.2 ± 7.2

69.7 ± 8.6

< 0.001

Duration of illness (mean ± SD)

5.6 ± 3.2

5.9 ± 3.3

0.115

5.5 ± 3.1

5.9 ± 3.4

0.481

Duration of treatment (mean ± SD)

4 ± 2.9

4.6 ± 2.5

0.292

4.1 ± 2.7

4.8 ± 2.5

0.066

Hoehn and Yahr (H Y) stage

 Stage 1.5

0

7

0.014

1

6

0.038

 Stage 2.5

3

18

5

16

 Stage 3

12

15

16

11

 Stage 4

5

4

4

5

UPDRS: total score

122.6 ± 30.2

69.8 ± 33.7

< 0.001

114.7 ± 29.8

66.9 ± 35.7

< 0.001

 Mental

9.1 ± 2.8

5 ± 2.1

8.6 ± 2.6

4.6 ± 2.1

 ADL

33.4 ± 10.5

19.8 ± 10.5

30.9 ± 9.8

19.4 ± 11.5

 Motor

73.6 ± 15.7

41.4 ± 20.8

67 ± 16.5

40.9 ± 23.3

 Complications of therapy

6.6 ± 5.6

3.6 ± 3.5

8.2 ± 4.7

2 ± 1.6

MMSE

21.5 ± 4.9

25.2 ± 3.8

0.001

24.4 ± 4.1

23.8 ± 4.7

0.599

  1. Depression and anxiety were diagnosed using DSM-IV TR criteria and scored using Hamilton Depression and Hamilton Anxiety Rating Scales (HAM-D and HAM-A). PD Parkinson’s disease, UPDRS Unified Parkinson’s Disease Rating Scale, ADL activity of daily living