Characteristic | PD with depression N = 20 | PD without depression N = 44 | P value | PD with anxiety N = 26 | PD without anxiety N = 38 | P value |
---|---|---|---|---|---|---|
Age at onset (mean ± SD) | 64.4 ± 7.8 | 67.1 ± 9.5 | 0.155 | 61.2 ± 7.2 | 69.7 ± 8.6 | < 0.001 |
Duration of illness (mean ± SD) | 5.6 ± 3.2 | 5.9 ± 3.3 | 0.115 | 5.5 ± 3.1 | 5.9 ± 3.4 | 0.481 |
Duration of treatment (mean ± SD) | 4 ± 2.9 | 4.6 ± 2.5 | 0.292 | 4.1 ± 2.7 | 4.8 ± 2.5 | 0.066 |
Hoehn and Yahr (H Y) stage | ||||||
Stage 1.5 | 0 | 7 | 0.014 | 1 | 6 | 0.038 |
Stage 2.5 | 3 | 18 | 5 | 16 | ||
Stage 3 | 12 | 15 | 16 | 11 | ||
Stage 4 | 5 | 4 | 4 | 5 | ||
UPDRS: total score | 122.6 ± 30.2 | 69.8 ± 33.7 | < 0.001 | 114.7 ± 29.8 | 66.9 ± 35.7 | < 0.001 |
Mental | 9.1 ± 2.8 | 5 ± 2.1 | 8.6 ± 2.6 | 4.6 ± 2.1 | ||
ADL | 33.4 ± 10.5 | 19.8 ± 10.5 | 30.9 ± 9.8 | 19.4 ± 11.5 | ||
Motor | 73.6 ± 15.7 | 41.4 ± 20.8 | 67 ± 16.5 | 40.9 ± 23.3 | ||
Complications of therapy | 6.6 ± 5.6 | 3.6 ± 3.5 | 8.2 ± 4.7 | 2 ± 1.6 | ||
MMSE | 21.5 ± 4.9 | 25.2 ± 3.8 | 0.001 | 24.4 ± 4.1 | 23.8 ± 4.7 | 0.599 |