| Total (n = 165) | Controlled (< 1 seizure per month), n = 40 | Uncontrolled (≥ 1 seizure per month), n = 125 | P value | ||
---|---|---|---|---|---|---|
Sex | Male | 99 (60%) | 25 (62.5%) | 74 (59.2%) | 0.711 | |
Female | 66 (40%) | 15 (37.5%) | 51 (40.8%) | |||
Age | Range, mean ± SD | 3–68, 29.9 ± 12.6 | 2–62, 34.7 ± 12.5 | 0.3–50, 28.4 ± 12.4 | 0.005* | |
Median | 28 (20–37) | 35 (27–40) | 27 (19–36) | |||
Age of onset | Mean ± SD | 16.1 ± 13.6 | 22.7 ± 15.7 | 14 ± 12.1 | 0.001* | |
Median | 13 (5–24) | 22.5 (8–34.5) | 11 (4–20) | |||
Duration of epilepsy | Mean ± SD | 13.9 ± 9.9 | 12 ± 9.5 | 14.5 ± 10 | 0.152 | |
Median | 13 (5.7–20.5) | 11.5 (3–18) | 13 (6–21) | |||
Family history | Yes | 22 (13.3%) | 2 (9.1%) | 20 (90.9%) | 0.075 | |
No | 143 (86.7%) | 38 (26.6%) | 105 (73.4%) | |||
History of status epilepticus | Yes | 22 (13.3%) | 8 (36.4%) | 14 (63.6%) | 0.154 | |
No | 143 (86.7%) | 32 (22.4%) | 111 (77.6%) | |||
History of febrile seizures | Yes | 12 (7.3%) | 4 (33.3%) | 8 (66.7%) | 0.487 | |
No | 153 (92.7%) | 36 (23.5%) | 117 (76.5%) | |||
Mentality | Normal | 139 (84.2%) | 36 (25.9%) | 103 (74.1%) | 0.251 | |
Abnormal | 26 (15.8%) | 4 (15.4%) | 22 (84.6%) | |||
Type of seizure | Generalized | Motor | 33 (20%) | 9 (35%) | 24 (65%) | 0.413 |
Non-motor | 33 (20%) | 9 (35%) | 24 (65%) | |||
Focal | Motor | 120 (72.7%) | 30 (25%) | 90 (75%) | 0.679 | |
Non-motor | 8 (4.8%) | 1 (12.5%) | 7 (87.5%) | |||
Aware | 90 (54.5%) | 20 (22.2%) | 70 (77.8%) | 0.417 | ||
Impaired awareness | 38 (23%) | 11 (28.9%) | 27 (71.1%) | |||
To BTC | 99 (60%) | 28 (28.3%) | 71 (71.7%) | 0.047* | ||
Not to BTC | 29 (17.6%) | 3 (10.3%) | 26 (89.7%) | |||
EEG | Normal | 53 (32.1%) | 14 (25.9%) | 40 (74.1%) | 0.160 | |
Abnormal | 74 (44.9%) | 11 (15.7%) | 59 (84.3%) | |||
No. of antiepileptic drugs | 1 | 32 (19.4%) | 20 (50%) | 12 (9.6%) | < 0.001* | |
2 | 87 (52.7%) | 17 (42.5%) | 70 (56%) | 0.137 | ||
3 or more | 46 (27.9%) | 3 (7.5%) | 43 (34.4%) | 0.001* | ||
Type of antiepileptic | 1st generation | 57 (34.5%) | 24 (60%) | 33 (26.4%) | < 0.001* | |
2nd generation | 12 (7.3%) | 5 (12.5%) | 7 (5.6%) | 0.165 | ||
1st + 2nd | 96 (58.2%) | 11 (27.5%) | 85 (68%) | < 0.001* |