Table 4 Uni- and multivariate analysis to estimate the effects of consanguinity and family history on MMP2 levels
Variables | Controls (n = 50) | Patients (n = 100) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|---|
p value | OR (95% CI) | p value | OR (95% CI) | |||
Consanguinity | Â | Â | < 0.001 | 1.0 6.29 (2.76-14.33) | < 0.001 | 1.0 6.32 (2.68-14.87) |
 No | 41 (82%) | 42 (42%) | ||||
 Yes | 9 (18%) | 58 (58%) | ||||
Family history | Â | Â | < 0.001 | 1.0 13.02 (1.69-99.9) | 0.016 | 1.0 12.88 (1.6-103.4) |
 No | 50 (100%) | 76 (76%) | ||||
 Yes | 0 (0%) | 21 (21%) | ||||
MMP-2 (ng/ml) | Â | Â | 0.011 | 1.0 2.57 (1.24-5.34) | 0.048 | 1.0 2.28 (1.0-5.14) |
 ≤ 8.27 | 36 (72%) | 50 (50%) | ||||
 > 8.27 | 14 (28%) | 50 (50%) | ||||