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Table 3 Serum MMP-2 and HMGB1 in patients with refractory epilepsy and controls

From: Diagnostic value of matrix metalloproteinase-2 and high mobility group box 1 in patients with refractory epilepsy

Biochemical parameter

Controls (n = 50)

Epileptic patients (n = 100)

p value

Controlled (n = 60)

Refractory (n = 40)

MMP-2 (ng/ml)

   

0.036

Mean ± SD

14.69 ± 11.54

12.0 ± 28.19

5.44 ± 6.52

Median

14.75a

11.25b

9.0b

IQR

11.73

10.19

10.77

HMGB1 (ng/ml)

   

0.572

Mean ± SD

5.93 ± 2.92

6.19 ± 4.71

5.39 ± 4.22

Median

6.8

7.2

6.03

IQR

3.13

4.01

3.36

  1. MMP-2 matrix metalloprotinase-2, HMGB1 high-mobility group box-1, IQR interquartile range, different small letters indicated significant differences
  2. The comparison was performed using Kruskal-Wallis non-parametric test