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Table 2 Demographic and clinical data of epileptic patients

From: Diagnostic value of matrix metalloproteinase-2 and high mobility group box 1 in patients with refractory epilepsy

Variables

Epileptic patients on AEDs

p value

Controlled (n = 60)

Refractory (n = 40)

Age, years

≤ 10

12 (20%)

10 (25%)

0.554

11-20

28 (46.67%)

11 (27.5%)

0.054

21-30

12 (20%)

15 (37.5%)

0.053

≥ 31

8 (13.33%)

4 (10%)

0.615

Gender

Male

28 (46.67%)

21 (52.5%)

0.568

Female

32 (53.33%)

19 (47.5%)

Family history

No

11 (18.33%)

10 (25%)

0.423

Yes

49 (81.67%)

30 (75%)

Consanguinity

No

26 (43.33%)

16 (40%)

0.741

Yes

34 (65.67)

24 (60%)

Type of epilepsy

Focal

28 (46.67%)

17 (42.5%)

0.682

GTC

21 (35%)

14 (35%)

1.0

Others

11 (18.33%)

9 (22.5%)

0.61

Seizure frequency

Daily

12 (20%)

28 (70%)

0.001

1-5 times/week

14 (23.33%)

12 (30%)

0.457

1-5 times/month

15 (25%)

0 (0%)

0.001

< Once a month

19 (31.67%)

0 (0%)

0.001

Aggravating factors

No specific factor

26 (43.33%)

14 (35%)

0.405

Tiredness

10 (16.67%)

5 (12.5%)

0.568

Stress

5 (8.33%)

3 (7.5%)

0.88

Sadness

4 (6.67%)

4 (10%)

0.547

Fever

9 (15%)

4 (10%)

0.466

Others (cell phone)

6 (10%)

10 (25%)

0.045

Duration of illness (years)

5.92 ± 4.64

10.78 ± 7.88

0.041‡

5.0 (1-7)

10 (1-35)

 

Residence

Urban

43 (71.67%)

33 (82.5%)

0.214†

Rural

17 (28.33%)

7 (17.5%)

BMI (kg/m2)

23.29 ± 6.81

23.42 ± 7.64

0.914

  1. AEDs antiepileptic drugs, GTC generalized tonic-clonic, BMI body mass index
  2. †Student’s t test
  3. ‡Mann-Whitney U test