Outcome predictors of intravenous thrombolytic therapy in acute ischemic stroke patients: an Egyptian center experiences

Table 4 Univariate and multivariate analysis between study variable (stroke illness and ICH following IV rtPA) and poor functional outcome

	Univariate		^#Multivariate
	P	OR (95% C.I)	P	OR (95% C.I)
NIHSS score 24 h after IV rtPA	< 0.001^*	3.63^*(2.10–6.27)	0.003^*	8.039^*(2.01–32.07)
Categorical classification of stroke severity at time of admission	0.001^*	9.338^*(3.31–26.32)	0.647	4.34 (0.008–2321.5)
NIHSS score at time of admission	< 0.001^*	1.477^*(1.297–1.68)	0.148	0.511 (0.206–1.26)
Stroke lesion location in posterior circulation territory	< 0.001^*	6.314^*(2.411–16.53)	0.206	13.36 (0.24–740.6)
Increased pulsatility index at the same side of stroke lesion	< 0.001^*	52.01^*(17.77–152.17)	0.038^*	42.48^* (1.24–1455.0)
Time of receiving IV rtPA from stroke onset (3–4.5 h)	0.647	0.864 (0.436–1.711)
Intracerebral hemorrhage following IV rtPA (symptomatic +asymptomatic)	0.001^*	29.10^* (3.66–231.9)	0.570	0.034 (0.0–3907.1)