Skip to main content

Table 2 General characteristics of the studies used in the systematic review

From: Olanzapine in the treatment of anorexia nervosa: a systematic review

Name of studyType of studyNumber of participants and age (year)Therapy detailsEfficiency
Hansen L [17]Case report1 (age: 49)10 mg/day olanzapineEffective
La Via et al. [18]Case series2 (age: 15 and 27)5 mg/day olanzapineEffective
Jensen and Mejhede [19]Case series3 (age: 30, 34, 50)5-10 mg/day olanzapine + psychotherapyEffective
Mehler et al. [20]Case series5 (age: 12, 17)Variable doses of olanzapine ± psychotherapyEffective
Powers et al. [21]Case control study14 (age:14-56 with mean age of 26.8)10 mg/day olanzapine for 10 weeks + psychotherapyEffective
Ercan et al. [22]Case report1 (age: 15)20 mg/day olanzapineEffective
Dennis et al. [23]Case series5 (age: 12-18)Variable doses of olanzapine ± psychotherapyEffective
Brambilla et al. [24]Randomized placebo-controlled trial20 (mean age: 23 ± 4.8)2.5 mg/day for 2 months and 5 mg/day for 2 monthsIneffective
Bissada et al. [25]Randomized placebo-controlled trial34 (mean age: 29.67 ± 11.59)Variable doses of olanzapine for 10-week periodEffective
Brown University (17) [26]Case control study13 (age non-specified)2.5 mg olanzapine for 6 weeksEffective
Leggero et al. [27]Case control study13 (mean age: 13.7 ± 2.3)Low dose olanzapine for 6 months + psychotherapyEffective
Capasso et al. [28]Case report1 (age: 19)2.5 mg olanzapine for 1 month and 5 mg for 3 monthsEffective
Attia et al. [29]Randomized, double blind, placebo-controlled trial23 (mean age: 27.7 ± 9.1)2.5-10 mg olanzapine for 8 weeks ± anti-depressantsEffective
Kafantaris et al. [30]Randomized, double blind, placebo-controlled trial15 (mean age: 17.1 ranging between 12 and 21)Low dose olanzapine for 10 weeksNot effective
Pirkalani and Anorexia [31]Case control study27 (age non-specified)2.5 mg olanzapine for 6 weeks + citalopram + vitamin B6Effective
Bangratz et al. [32]Case control study16 (age: 11-17)5-10 mg olanzapine for 5 weeksEffective
Duvvuri et al. [33]Case report1 (age: 12)2.5 mg olanzapine for 36 weeksEffective
Haruta et al. [34]Case report1 (age: 36)20 mg day paroxetine +2.5 mg day olanzapine + psychotherapyNot effective in weight restoration, hypoglycemia develops
Kesic et al. [35]Case control study24 (age: 14-20)2.5-7.5 mg olanzapine for 3-42 weeks ± psychotherapy ± anti-depressantsEffective
Alwazeer et al. [36]Case report1 (age: 16)2.5-7.5 mg olanzapine for 4 weeksEffective in weight restoration, heart block develops
Ayyıldız et al. [37]Case report1 (age: 17)5 mg day olanzapine + psychotherapyEfficiency unknown, neuroleptic malignant syndrome develops on day 2
Himmerich et al. [38]Case control study12 (age: 18-60)8 weeks of olanzapineEffective
Spettigue et al. [39]Case control study32 (age: 11-17)Open label trial with various dosage and durationEffective
Attia et al. [40]Randomized double-blind placebo-controlled trial152 (age: 18-65)2.5-10 mg olanzapine for 16 weeksEfficient in terms of weight restoration