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Table 5 Impact of patient diagnosis and types of chemotherapy on the score of each component of cognitive functions

From: Chemotherapy-induced cognitive impairment in hematological malignancies

Variables Executive Naming Attention Language Abstraction Delayed recall Orientation Total score
Diagnosis AML 3.42 ± 1.07 2.87 ± 0.45 3.55 ± 0.89 2.42 ± 0.83 0.97 ± 0.65 4.06 ± 1.26 5.64 ± 0.83 22.95 ± 5.21
ALL 3.93 ± 0.59 3.00 ± 0.00 4.20 ± 0.94 2.66 ± 0.48 0.93 ± 0.59 4.40 ± 1.24 5.80 ± 4.14 24.93 ± 3.77
CML 4.43 ± 0.51 3.00 ± 0.00 3.81 ± 0.65 2.87 ± 0.34 1.37 ± 0.50 4.68 ± 0.47 6.00 ± 0.00 26.18 ± 1.94
CLL 3.45 ± 0.88 3.00 ± 0.00 3.80 ± 1.05 2.70 ± 0.73 1.05 ± 0.60 4.00 ± 1.07 5.70 ± 0.73 23.70 ± 4.53
MDS 2.00 ± 0.00 3.00 ± 0.00 3.00 ± 0.00 2.00 ± 0.00 0.00 ± 0.00 4.00 ± 0.00 6.00 ± 0.00 20.00 ± 0.00
Lymphoma 3.32 ± 0.94 3.00 ± 0.00 3.92 ± 0.64 2.68 ± 0.47 1.20 ± 0.40 4.48 ± 0.51 6.00 ± 0.00 24.60 ± 1.84
MM 3.37 ± 0.96 3.00 ± 0.00 3.48 ± 0.64 2.44 ± 0.69 1.14 ± 0.36 4.03 ± 1.01 5.92 ± 0.26 23.40 ± 3.19
ANOVA F 4.49 1.45 2.11 1.60 2.84 1.37 1.79 2.06
p value < 0.001 0.19 0.05 0.15 0.01 0.23 0.10 0.06
CT protocol Intensified CT 3.51 ± 0.99 2.89 ± 0.41 3.69 ± 0.93 2.48 ± 0.78 0.96 ± 0.66 4.16 ± 1.27 5.66 ± 0.76 23.37 ± 5.02
TKIs 4.30 ± 0.48 3.00 ± 0.00 3.76 ± 0.72 2.84 ± 0.37 1.46 ± 0.51 4.61 ± 0.50 6.00 ± 0.00 26.00 ± 2.12
Velcade based 3.37 ± 0.96 3.00 ± 0.00 3.48 ± 0.64 2.44 ± 0.69 1.14 ± 0.36 4.03 ± 1.01 5.92 ± 0.26 23.40 ± 3.19
Others 3.46 ± 1.00 3.00 ± 0.00 3.85 ± 0.83 2.66 ± 0.58 1.07 ± 0.50 4.27 ± 0.83 5.88 ± 0.46 24.22 ± 3.33
ANOVA F 3.18 2.09 1.21 1.72 3.04 1.03 2.55 1.80
p value 0.02 0.10 0.30 0.16 0.03 0.38 0.05 0.15