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Table 5 Montreal cognitive assessment in MS subtypes with cognitive impairment

From: Correlation between brain magnetic resonance imaging, cognitive dysfunction and physical dysability in multiple sclerosis

 

RRMS (N = 27)

SPMS (N = 4)

CIS (N = 1)

p

Visuospatial/executive

 Trail making (executive)

0.56 ± 0.51

0.5 ± 0.58

0 ± 0

0.571

 Cube (visuoconstructional)

0.7 ± 0.47

0.5 ± 0.58

1 ± 0

0.59

 Clock (visuoconstructional)

2.52 ± 0.75

2.5 ± 1

3 ± 0

0.831

Naming

2.19 ± 0.74

2.5 ± 0.58

2 ± 0

0.687

Attention

 Digit span (sustained attention)

1.74 ± 0.45

0.75 ± 0.5

2 ± 0

0.001

 Vigilance (concentration)

0.96 ± 0.19

1 ± 0

1 ± 0

0.917

 Serial 7s (working memory)

1.52 ± 1.01

1.25 ± 1.26

2 ± 0

0.792

Language

 Repetition

0.56 ± 0.51

0.5 ± 0.58

0 ± 0

0.571

 Fluency

0.93 ± 0.27

1 ± 0

1 ± 0

0.181

Abstraction (similarities)

0.3 ± 0.47

0.25 ± 0.5

1 ± 0

0.338

Delayed recall (episodic memory)

1.48 ± 1.4

1.25 ± 1.26

2 ± 0

0.883

Orientation

1.22 ± 0.75

1 ± 0

1 ± 0

0.815

Total MoCA score

20.56 ± 3.8

18.75 ± 3.2

22 ± 0

0.609

  1. p significant if < 0.05
  2. N number, RRMS relapsing-remittent multiple sclerosis, SPMS secondary progressive multiple sclerosis, CIS clinically isolated syndrome