Skip to main content

Table 3 Comparison between the three studied groups according to given time, time spent in target quadrant, total distance swum, distance in target quadrant, and escape trials (water maze test)

From: The potential value of capsaicin in modulating cognitive functions in a rat model of streptozotocin-induced Alzheimer’s disease

Water maze test Group I Group II Group III F p
Given time (seconds)
 Min.–max. 60.0–60.0 60.0–60.0 60.0–60.0
 Mean ± SD 60.0 ± 0.0 60.0 ± 0.0 60.0 ± 0.0
Time spent in target quadrant (%)
 Min.–max. 50.0–71.7 31.7–46.7 53.3–80.0 22.166* < 0.001*
 Mean ± SD 59.2 ± 6.7 39.3a ± 5.6 66.7 ab ± 8.9
Total distance swum (cm)
 Min.–max. 75.0–77.5 79.0–79.8 73.0–77.0 74.652* < 0.001*
 Mean ± SD 76.2 ± 0.9 79.4a ± 0.3 74.9ab ± 1.1
Distance swum in target quadrant (%)
 Min.–max. 34.2–44.5 20.7–31.4 45.0–53.7 98.371* < 0.001*
 Mean ± SD 37.8 ± 4.3 23.9a ± 3.5 47.8ab ± 2.5
Escape trials
 Min.–max. 0.0–3.0 4.0–10.0 1.0–4.0 18.551* < 0.001*
 Mean ± SD 1.8 ± 1.3 6.0a ± 2.0 2.5b ± 0.8
  1. Group I negative controls; Group II STZ-induced AD, capsaicin untreated group (positive controls); Group III STZ-induced AD+ capsaicin treatment group. Normally quantitative data was expressed in mean ± SD and was compared using F test (ANOVA). F, p: F and p values for ANOVA test. Sig. between groups was done using post hoc test (LSD)
  2. *Statistically significant at p ≤ 0.05
  3. aSignificantly different from the negative controls (group I)
  4. bSignificantly different from the positive controls (STZ-induced AD, capsaicin untreated) (group II)