Table 2 Variants identified in common form of migraine and replicated in various studies
From: Role of single nucleotide polymorphisms (SNPs) in common migraine
SNPs | Chromosome locus | Gene | Biochemical markers |
|---|---|---|---|
rs1835740 | 8q22.1 | MTDH | Glutamate |
rs1801133 | – | – | – |
rs1801131 | 1p36.3 | MTHFR | Homocysteine |
rs11172113 | 12q13.3 | LRP1 | NMDA glutamate |
rs10166942 | 2q37 | TRPM8 | Pain sensor protein |
rs2651899 | 1p36.32 | PRDM16 | TGF-β signaling |
rs4379368 | 7p14 | C7orf10 | Glutaric acid |
rs10504861 | 8q21 | MMp16 | MT3-MMP protein |
rs10915437 | 1p36 | AJAP1 | DFFB, TP73, and CEP104 protein |
rs12134493 rs2078371 | 1p13 | TSPAN2 | Transmembrane protein |
rs13208321 | 6q16 | FHL5 | CREM, CREB |
rs3790455 | 1q22 | MEF2D | – |
rs7640543 | 3p24.1 | TGFBR2 | – |
rs9349379 | 6p21 | PHACTR1 | PP1 |
rs6478241 | 9q33.1 | ASTN2 | – |