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Table 2 Comparison between patient subgroups regarding serum laboratory markers of bone health

From: Evaluation of bone health among epileptic patients using biochemical markers and DEXA scan: an Egyptian study

Variables Normal (a) (N = 8) Osteopenia (b) (N = 17) Osteoporosis (c) (N = 5) ρ value Pair-wise comparisons
(a) × (b) (a) × (c) (b) × (c)
Serum calcium (mg/dl) Mean ± SD 8.9 ± 0.4 8.6 ± 0.4 7.8 ± 0.2 0.0001** 0.09 0.0001** 0.003**
Range 8.2–9.5 8.0–9.2 7.5–8.0
Serum phosphorus (mg/dl) Mean ± SD 4.3 ± 0.4 3.2 ± 0.3 3.0 ± 0.3 0.0001** 0.0001** 0.0001** 0.2
Range 3.7–4.9 2.8–3.9 2.7–3.5
Alkaline phosphatase (IU/l) Mean ± SD 153.4 ± 41.9 171.5 ± 46.6 194.4 ± 30.3 0.267 0.0001** 0.0001** 0.0001**
Range 102.6–206.2 108.5–246.2 142.1–221.3
Parathormone (ng/ml) Mean ± SD 82.2 ± 19.7 82.5 ± 30.2 99.4 ± 31.2 0.0001** 0.95 0.0001** 0.0001**
Range 50.7–105.2 36.4–114.2 51.4–128.5
Vitamin D (nmol/l) Mean ± SD 30.5 ± 2.3 20.7 ± 5.1 11.7 ± 1.2 0.0001** 0.0001** 0.0001** 0.0001**
Range 27.2–32.5 13.1–29.2 10.2–12.9
  1. Subgroups: (a) normal, (b) osteopenia, and (c) osteoporosis
  2. Ρ value > 0.05 = non-significant; **ρ value < 0.01 highly significant