Sleep and psychiatric abnormalities in Gullian Barré Syndrome

Bahnasy, Wafik Said; El-Heneedy, Yasser Abo Elfotoh; El-Shamy, Ahmed Mohamed; Badr, Marwa Yassin; Amer, Reham Ahmed; Ibrahim, Ibrahim Salah Eldeen

doi:10.1186/s41983-018-0007-1

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Table 1 Comparison between Gullian Barré patients and control subjects at initial assessment

From: Sleep and psychiatric abnormalities in Gullian Barré Syndrome

	Patients		Control	ANOVA
		Mean ± SD	Mean ± SD	f value	p value
Overall Disability Sum Score	Early	5.95 ± 0.82	0.7 0 ± 0.82	156.47	> 0.0001*
Overall Disability Sum Score	Late	4.15 ± 0.67	0.7 0 ± 0.82	156.47	> 0.0001*
Neuropathy Pain Scale	Early	17.35 ± 8.28	9.0 ± 3.59	10.09	0.004*
Neuropathy Pain Scale	Late	9.15 ± 5.02	9.0 ± 3.59	10.09	0.998
Hamilton Anxiety Scale	Early	25.9 ± 5.7	7.7 ± 2.16	22.5	> 0.0001*
Hamilton Anxiety Scale	Late	21.15 ± 5.54	7.7 ± 2.16	22.5	> 0.0001*
MADRS	Early	18.9 ± 9.96	7.4 ± 5.08	6.74	0.002*
MADRS	Late	15.55 ± 7.12	7.4 ± 5.08	6.74	0.033*
Mean sleep latency of MSLT (min)	Early	11.79 ± 3.97	16.64 ± 2.2	6.79	0.002*
Mean sleep latency of MSLT (min)	Late	14.23 ± 3.45	16.64 ± 2.2	6.79	0.185
Total sleep time (hours)	Early	5.28 ± 0.43	7.29 ± 0.33	70.49	> 0.0001*
Total sleep time (hours)	Late	5.64 ± 0.49	7.29 ± 0.33	70.49	> 0.0001*
Wake after sleep onset (hours)	Early	2.91 ± 0.588	0.85 ± 0.34	64.66	> 0.0001*
Wake after sleep onset (hours)	Late	2.53 ± 0.41	0.85 ± 0.34	64.66	> 0.0001*
Sleep efficiency (%)	Early	62.56 ± 5.93	86.38 ± 4.22	74.44	> 0.0001*
Sleep efficiency (%)	Late	67.53 ± 4.57	86.38 ± 4.22	74.44	> 0.0001*
SSTI (No of sleep stages/h)	Early	21.9 ± 6.51	8.6 ± 1.6	24.5	> 0.0001*
SSTI (No of sleep stages/h)	Late	19.74 ± 4.36	8.6 ± 1.6	24.5	> 0.0001*
Apnea hypopnea index (/hour)	Early	19.11 ± 7.75	5.67 ± 5.46	16.64	> 0.0001*
Apnea hypopnea index (/hour)	Late	18.2 ± 5.15	5.67 ± 5.46	16.64	> 0.0001*
Pulse Transit Time (msec)	Early	184.6 ± 23.2	241.4 ± 13.2	13.6	> 0.0001*
Pulse Transit Time (msec)	Late	232.3 ± 12.3	241.4 ± 13.2	13.6	> 0.0001*
Arousal index (/hour)	Early	37.6 5 ± 12.69	5.5 ± 2.63	33.64	> 0.0001*
Arousal index (/hour)	Late	35.4 ± 10.98	5.5 ± 2.63	33.64	> 0.0001*
Snore Index (/hour)	Early	299.3 ± 142.25	29.1 ± 21.89	22.53	> 0.0001*
Snore Index (/hour)	Late	234.45 ± 81.66	29.1 ± 21.89	22.53	> 0.0001*
Periodic limb movements index (/hour)	Early	46.35 ± 22.61	9.9 ± 3.66	13.29	> 0.0001*
Periodic limb movements index (/hour)	Late	41.0 ± 18.92	9.9 ± 3.66	13.29	> 0.0001*

Early after admission and before immunotherapy, Late 1 month after immunotherapy, MADRS Montgomery–Åsberg Depression Rating Scale, MSLT multiple sleep latency test, SSTI sleep stage transition index
*Significant

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